BRN 4488383 manufacturers
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| | BRN 4488383 Basic information |
| Product Name: | BRN 4488383 | | Synonyms: | BRN 4488383;3-[4'-Bromo(1,1'-biphenyl)-4-yl]-4-hydroxy-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-(4'-bromo[1,1'-biphenyl]-4-yl)-4-hydroxy-;Glycolic acid oxidase inhibitor 1;4-(4'-Bromo-4-biphenylyl)-5-hydroxy-1H-pyrrole-2,3-dione | | CAS: | 77529-42-1 | | MF: | C16H10BrNO3 | | MW: | 344.16 | | EINECS: | | | Product Categories: | | | Mol File: | 77529-42-1.mol |  |
| | BRN 4488383 Chemical Properties |
| Melting point | 326-328 °C (decomp) | | Boiling point | 528.9±50.0 °C(Predicted) | | density | 1.641±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : ≥ 137 mg/mL (398.07 mM) | | pka | 4.50±1.00(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | BRN 4488383 Usage And Synthesis |
| Uses | Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV. | | in vivo | Glycolic acid oxidase inhibitor 1 inhibits oxalate biosynthesis in isolated perfused rat liver. Glycolate oxidase inhibitors provide a specific approach to the prevention and treatment of calcium oxalate renal lithiasis[1]. | | References | [1] Cragoe Jr., Edward J, et al. 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione compounds, process for their preparation and pharmaceutical compositions containing the same.EP0021228A1. |
| | BRN 4488383 Preparation Products And Raw materials |
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