2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 3-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl ester

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2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 3-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl ester Suppliers list
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Email: klq@cw-bio.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 3-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl ester manufacturers

  • HDAC-IN-42
  • HDAC-IN-42 pictures
  • $3520.00
  • 2026-04-20
  • CAS:2454024-18-9
  • Purity:
  • Supply Ability: 10g
2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 3-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl ester Basic information
Product Name:2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 3-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl ester
Synonyms:2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 3-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl ester;HDAC-IN-42
CAS:2454024-18-9
MF:C20H15NO7
MW:381.34
EINECS:
Product Categories:
Mol File:2454024-18-9.mol
2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 3-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl ester Structure
2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 3-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl ester Chemical Properties
density 1.430±0.06 g/cm3(Predicted)
pka8+-.0.23(Predicted)
Safety Information
MSDS Information
2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 3-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl ester Usage And Synthesis
UsesHDAC-IN-42 (compound 14f) is a potent and selective HDAC inhibitor with IC50 values of 0.19 and 4.98 μM for HDAC1 and HDAC6, respectively. HDAC-IN-42 shows anticancer and anti-proliferative activity. HDAC-IN-42 induces apoptosis and cell cycle arrest at G2/M phase[1].
IC 50HDAC1: 0.19 μM (IC50); HDAC6: 4.98 μM (IC50)
References[1] Ding J, et al. Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities. Bioorg Chem. 2020 Aug;101:104023. DOI:10.1016/j.bioorg.2020.104023
2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 3-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl ester Preparation Products And Raw materials
Tag:2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 3-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl ester(2454024-18-9) Related Product Information
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