Benzenesulfonamide, 4-[(1E)-2-[6-amino-2-(4-methylphenyl)-1H-imidazo[1,2-b]pyrazol-7-yl]diazenyl]-

Benzenesulfonamide, 4-[(1E)-2-[6-amino-2-(4-methylphenyl)-1H-imidazo[1,2-b]pyrazol-7-yl]diazenyl]- Suppliers list

Company Name:	TargetMol Chemicals Inc.
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Email:	marketing@targetmol.com
Products Intro:	Product Name:Carbonic anhydrase inhibitor 14 CAS:2410402-75-2 Package:50mg;1980USD\|25mg;1520USD\|100mg;2500USD

Company Name:	Tianjin Kailiqi Biotechnology Co., Ltd.
Tel:	15076683720
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Products Intro:	Product Name:Benzenesulfonamide, 4-[(1E)-2-[6-amino-2-(4-methylphenyl)-1H-imidazo[1,2-b]pyrazol-7-yl]diazenyl]- CAS:2410402-75-2 Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.

Company Name:	Nantong Hanfang Biotechnology Co. , Ltd.
Tel:	hanfangpharma@126.com; 18616537568
Email:	hanfangpharma@126.com
Products Intro:	Product Name:Benzenesulfonamide, 4-[(1E)-2-[6-amino-2-(4-methylphenyl)-1H-imidazo[1,2-b]pyrazol-7-yl]diazenyl]- CAS:2410402-75-2 Purity:98%+ Package:1g；5g；10g；100g; 1kg

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Email:	marketing@targetmol.cn
Products Intro:	Product Name:Carbonic anhydrase inhibitor 14 CAS:2410402-75-2 Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500

Benzenesulfonamide, 4-[(1E)-2-[6-amino-2-(4-methylphenyl)-1H-imidazo[1,2-b]pyrazol-7-yl]diazenyl]- manufacturers

Benzenesulfonamide, 4-[(1E)-2-[6-amino-2-(4-methylphenyl)-1H-imidazo[1,2-b]pyrazol-7-yl]diazenyl]- Basic information

Product Name:	Benzenesulfonamide, 4-[(1E)-2-[6-amino-2-(4-methylphenyl)-1H-imidazo[1,2-b]pyrazol-7-yl]diazenyl]-
Synonyms:	Benzenesulfonamide, 4-[(1E)-2-[6-amino-2-(4-methylphenyl)-1H-imidazo[1,2-b]pyrazol-7-yl]diazenyl]-;Carbonic anhydrase inhibitor 14
CAS:	2410402-75-2
MF:	C18H17N7O2S
MW:	395.44
EINECS:
Product Categories:
Mol File:	2410402-75-2.mol

Benzenesulfonamide, 4-[(1E)-2-[6-amino-2-(4-methylphenyl)-1H-imidazo[1,2-b]pyrazol-7-yl]diazenyl]- Chemical Properties

density	1.57±0.1 g/cm3(Predicted)
pka	10.05±0.10(Predicted)

Safety Information

MSDS Information

Benzenesulfonamide, 4-[(1E)-2-[6-amino-2-(4-methylphenyl)-1H-imidazo[1,2-b]pyrazol-7-yl]diazenyl]- Usage And Synthesis

Uses	Carbonic anhydrase inhibitor 14 (Compound 8b) is a carbonic anhydrase (CA) inhibitor with Ki values of 1203, 99.7, 9.4 and 27.7 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. Carbonic anhydrase inhibitor 14 can also inhibit CDK2 with an IC50 of 20.3 μM. Carbonic anhydrase inhibitor 14 shows antitumor activity[1].
IC 50	CDK2: 20.3 μM (IC₅₀); hCA XII: 27.7 nM (Ki); hCA IX: 9.4 nM (Ki); hCA II: 99.7 nM (Ki); hCA I: 1203 nM (Ki)
References	[1] Said MA, et al. Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation. Eur J Med Chem. 2020 Mar 1;189:112019. DOI:10.1016/j.ejmech.2019.112019

Benzenesulfonamide, 4-[(1E)-2-[6-amino-2-(4-methylphenyl)-1H-imidazo[1,2-b]pyrazol-7-yl]diazenyl]- Preparation Products And Raw materials

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