3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2)

Request For Quotation
3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) Suppliers list
Company Name: Nanjing Chemlin Chemical Co., Ltd  
Tel: 025-83697070 13770331960
Email: info@chemlin.com.cn
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ：65489617 13301690235
Email: Sales@ATKchemical.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: Wuxi Donghe Pharmaceutical Technology Co., Ltd.  
Tel: 63313187 15358055255
Email: 63313187@qq.com

3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) manufacturers
3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) Basic information
Product Name:3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2)
Synonyms:3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2);DPTN dihydrochloride;N-(4-(3,5-Dimethylphenyl)-5-(pyridin-4-yl)thiazol-2-yl)nicotinamide dihydrochloride;DPTN 2HCL
CAS:325767-87-1
MF:C22H18N4OS.2ClH
MW:459.39
EINECS:
Product Categories:
Mol File:325767-87-1.mol
3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) Structure
3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) Chemical Properties
solubility Soluble to 20 mM in DMSO with gentle warming
form Solid
color Light yellow to yellow
Safety Information
MSDS Information
3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) Usage And Synthesis
UsesDPTN is a potent and selective human, mouse, and rat A3AR antagonist with Ki values of 1.65, 9.61, and 8.53nM, respectively[1].
Biological ActivityDPTN is a potent and selective A3 adenosine receptor antagonist (Ki values are in the range 0.36 - 1.65 nM (hA3AR) and 1.6 - 8.53 nM (rA3AR)). Reduces intrapulmonary pressure when combined with Dexamethasone .
IC 50hA3: 1.65 nM (Ki)
storageStore at -20°C
References[1] Zhan-Guo Gao, et al. Pharmacological characterization of DPTN and other selective A3 adenosine receptor antagonist. Purinergic Signal. 2021 Dec;17(4):737-746. DOI:10.1007/s11302-021-09823-5
3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) Preparation Products And Raw materials
Tag:3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2)(325767-87-1) Related Product Information
COH-29 N-[4-(3,5-Dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-3-pyridinecarboxamide N-(acenaphtho[1,2-d]thiazol-8-yl)acetamide Propanamide, N-(5-methyl-4-phenyl-2-thiazolyl)- N-(4-(4-Methylphenyl)(2,5-thiazolyl))-3-pyridylformamide N-[4-(2,4,6-Trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide