| Company Name: |
TargetMol
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400-821-0310 15002144251 |
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xuexiang.shao@tsbiochem.com |
| Products Intro: |
Product Name:ALEPH hydrochloride
CAS:61638-08-2
Package:50mg/RMB 13800
|
| Company Name: |
Cayman Chemical Company
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| Tel: |
800-364-9897 |
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sales@caymanchem.com |
| Products Intro: |
Product Name:ALEPH (hydrochloride)
CAS:61638-08-2
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| Company Name: |
Biorbyt Ltd.
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| Tel: |
+44 (0)1223 859 353 |
| Email: |
info@biorbyt.com |
| Products Intro: |
Product Name:ALEPH hydrochloride
CAS:61638-08-2
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:ALEPH (hydrochloride)
CAS:61638-08-2
|
|
| | ALEPH (hydrochloride) Basic information |
| Product Name: | ALEPH (hydrochloride) | | Synonyms: | ALEPH (hydrochloride);Benzeneethanamine, 2,5-dimethoxy-α-methyl-4-(methylthio)-, hydrochloride (1:1);4-Methylthio-2,5-dimethoxyamphetamine hydrochloride | | CAS: | 61638-08-2 | | MF: | C12H19NO2S.ClH | | MW: | 277.81 | | EINECS: | | | Product Categories: | | | Mol File: | 61638-08-2.mol |  |
| | ALEPH (hydrochloride) Chemical Properties |
| Melting point | 200-202 °C | | solubility | DMSO: soluble |
| | ALEPH (hydrochloride) Usage And Synthesis |
| Uses | ALEPH (hydrochloride) is the h5-HT2A and h5-HT2B partial agonist with the EC50 values of 10.3 nM and 19.2 nM, respectively. ALEPH (hydrochloride) causes head twitch response in mice (ED50: 0.80 mg/kg)[1]. | | IC 50 | Human 5-HT2A Receptor; human 5-HT2B Receptor | | References | [1] Halberstadt AL, et al. Use of the head-twitch response to investigate the structure-activity relationships of 4-thio-substituted 2,5-dimethoxyphenylalkylamines. Psychopharmacology (Berl). 2023 Jan;240(1):115-126. DOI:10.1007/s00213-022-06279-2
[2] ALEJANDRA GALLARDO-GODOY. Sulfur-Substituted α-Alkyl Phenethylamines as Selective and Reversible MAO-A Inhibitors: Biological Activities, CoMFA Analysis, and Active Site Modeling[J]. Journal of Medicinal Chemistry, 2005, 48 7: 2407-2419. DOI: 10.1021/jm0493109 |
| | ALEPH (hydrochloride) Preparation Products And Raw materials |
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