| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:BDM88855 hydrochloride
CAS:2892824-26-7
Package:50mg;10mg
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| Company Name: |
Biorbyt Ltd.
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| Tel: |
+44 (0)1223 859 353 |
| Email: |
info@biorbyt.com |
| Products Intro: |
Product Name:BDM88855 hydrochloride
CAS:2892824-26-7
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| | BDM88855 Hcl Basic information |
| Product Name: | BDM88855 Hcl | | Synonyms: | BDM88855 Hcl;BDM88855 hydrochloride;Quinoline, 3-chloro-2-(1-piperazinyl)-, hydrochloride (1:1) | | CAS: | 2892824-26-7 | | MF: | C13H14ClN3.ClH | | MW: | 284.18 | | EINECS: | | | Product Categories: | | | Mol File: | 2892824-26-7.mol |  |
| | BDM88855 Hcl Chemical Properties |
| | BDM88855 Hcl Usage And Synthesis |
| Uses | BDM88855 hydrochloride is an allosteric inhibitor for the homolog AcrB protein. BDM88855 hydrochloride can boost the antibacterial effect of a panel of antibiotics (eg: Oxacillin (HY-B0925A), Linezolid (HY-10394), Novobiocin (HY-B0425), etc.) on wild-type E. coli[1][2]. | | References | [1] Plé C, et al. Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps. Nat Commun. 2022 Jan 10;13(1):115. DOI:10.1038/s41467-021-27726-2
[2] Bera A, et al. Exploring transmembrane allostery in the MexB: DB08385 variant as a promising inhibitor-like candidate against Pseudomonas aeruginosa antibiotic resistance: a computational study. Phys DOI:10.1039/d4cp01620c |
| | BDM88855 Hcl Preparation Products And Raw materials |
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