| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Bermoprofen
CAS:78499-27-1
Purity:99.28% Package:1mg/RMB 833;5mg/RMB 1780;10mg/RMB 2980
|
bermoprofen manufacturers
- Bermoprofen
-
- $74.00
-
2026-07-17
- CAS:78499-27-1
- Purity: 99.28%
- Supply Ability: 10g
- Bermoprofen
-
- $74.00
-
2026-07-17
- CAS:78499-27-1
- Purity: 99.28%
- Supply Ability: 10g
|
| | bermoprofen Basic information |
| Product Name: | bermoprofen | | Synonyms: | 10,11-Dihydro-α,8-dimethyl-11-oxodibenz[b,f]oxepine-2-acetic acid;AD-1590;2-(8-Methyl-10,11-dihydro-11-oxodibenz(B,F)oxepin-2-yl)propionic;Brn 4815717;Propionic acid, 2-(8-methyl-10,11-dihydro-11-oxodibenz(B,F)oxepin-2-yl)-;10,11-DIHYDRO-α-8-DIMETHYL-11-OXO-DIBENZ(b,f)OXEPIN-2-ACETIC ACID;AD-1590|||AJ-1590 | | CAS: | 78499-27-1 | | MF: | C18H16O4 | | MW: | 296.32 | | EINECS: | | | Product Categories: | | | Mol File: | 78499-27-1.mol |  |
| | bermoprofen Chemical Properties |
| Melting point | 128-129° | | Boiling point | 397.92°C (rough estimate) | | density | 1.1874 (rough estimate) | | refractive index | 1.5400 (estimate) | | storage temp. | Store at -20°C | | form | Solid | | color | Off-white to light yellow |
| Toxicity | LD50 in mice, rats (mg/kg): 500, 147 orally (Nakamura) |
| | bermoprofen Usage And Synthesis |
| Originator | Bermoprofen,ZYF Pharm Chemical | | Definition | ChEBI: Bermoprofen is a dibenzooxazepine. | | Manufacturing Process | A mixture of dl-2-[4-(2'-carboxymethyl-4'-methylphenoxy)phenyl]propionic
acid (15.3 g) and polyphosphoric acid (92 g) was heated with stirring at 110-
120°C for 2 hours. To the reaction mixture was added water and the resulting
mixture was extracted with chloroform. The organic layer was washed with
water, dried over anhydrous sodium sulfate and concentrated. The residue was
chromatographed on silica gel (75 g) using chloroform as an eluent to give a
crude product, which was recrystallized from toluene to give the dl-2-(8-
methyl-10,11-dihydro-11-oxodibenz[b,f]oxepin-2-yl)propionic acid (9.4 g,
65.3%), m.p. 128-129°C. | | Therapeutic Function | Antiinflammatory, Antipyretic |
| | bermoprofen Preparation Products And Raw materials |
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