A 31472

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A 31472 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
A 31472 Basic information
Product Name:A 31472
Synonyms:A 31472;(5S,4'R)-3-Chloro-N,N-dimethylspiro[5H-dibenzo[a,d]cycloheptene-5,1'-[2]cyclohexen]-4'-amine
CAS:69319-52-4
MF:C22H22ClN
MW:335.87
EINECS:
Product Categories:
Mol File:69319-52-4.mol
A 31472 Structure
A 31472 Chemical Properties
Boiling point 466.666±45.00 °C(Press: 760.00 Torr)(predicted)
density 1.199±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka9.722±0.20(predicted)
Safety Information
MSDS Information
A 31472 Usage And Synthesis
DescriptionA 31472 is a tetracyclic spiro amine that has affinity for dopamine D-2 receptors. These compounds are important for defining the pharmacophore for D-2 antagonist activity due to their limited conformational freedom.
UsesA31472 is a dopamine D-2 receptors antagonist that is promising for research of antipsychotic agents[1].
References[1] Froimowitz M, et al. Conformational properties of semirigid antipsychotic drugs: the pharmacophore for dopamine D-2 antagonist activity. J Med Chem. 1991 May;34(5):1707-14. DOI:10.1021/jm00109a026
A 31472 Preparation Products And Raw materials
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