| Company Name: |
J & K SCIENTIFIC LTD.
|
| Tel: |
18210857532; 18210857532 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:FluMiclorac-pentyl
CAS:87546-18-7
Purity:100 μg/ML in Methanol Package:1ML
|
| Company Name: |
Sichuan Kulinan Technology Co., Ltd
|
| Tel: |
400-1166-196 18981987031 |
| Email: |
cdhxsj@163.com |
| Products Intro: |
Product Name:FLUMICLORAC-PENTYL
CAS:87546-18-7
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg
|
|
| | FLUMICLORAC-PENTYL Basic information |
| Product Name: | FLUMICLORAC-PENTYL | | Synonyms: | SUMIVERDE;RESOURCE;FLUMICLORAC-PENTYL;flumiclorac-pentyl (bsi,pa iso,ansi);PENTYL2-CHLORO-4-FLUORO-5-(3,4,5,6-TETRAHYDROPHTHALIMIDO)PHENOXYACETATE;PENTYL2-CHLORO-4-FLUORO-5-(3,4,5,6-TETRAHYDROPHTHALIMIDO).;pentyl-[2-chloro-5-(cyclohex-1-ene-1,2-dicarboxamido)-4-fluorophenoxy] acetate;S 23031 | | CAS: | 87546-18-7 | | MF: | C21H23ClFNO5 | | MW: | 423.86 | | EINECS: | | | Product Categories: | | | Mol File: | 87546-18-7.mol |  |
| | FLUMICLORAC-PENTYL Chemical Properties |
| Melting point | 90-91℃ | | Boiling point | 558.0±50.0 °C(Predicted) | | density | d20 1.3316 | | storage temp. | 0-6°C | | pka | -2.32±0.20(Predicted) | | EPA Substance Registry System | Flumiclorac-pentyl (87546-18-7) |
| HS Code | 29251900 | | Toxicity | LD50 in rats (mg/kg): >5000 orally; >2000 dermally (Kamoshita) |
| | FLUMICLORAC-PENTYL Usage And Synthesis |
| Chemical Properties | Pure product is white powdery solid. Melting point 88.9～90.1℃, relative density 1.33(20℃), vapor pressure 1.0×10-5Pa (25℃), partition coefficient 4.99 (20℃), solubility at 25℃: methanol 47.8g/L, n-octanol 16.0g/L, acetone 590g/L, n-hexane 3.28g/L, water 0.189mg/L, half-life in water 6min (pH=9), 19h (pH=7), 42d (pH=5). 6min (pH=9), 19h (pH=7), 42d (pH=5). | | Uses | Herbicide. | | Uses | Flumiclorac-pentyl is a herbicide. | | Definition | ChEBI: Flumiclorac pentyl is a pyrroline. | | Synthesis | Flumiclorac-pentyl is produced via a 5–6 step synthesis that commences with the preparation of the hexahydrophthalic anhydride core through Diels-Alder cycloaddition of maleic anhydride with cis-1,3-butadiene under high-pressure conditions in benzene, followed by ring opening to the diacid and condensation with methylamine in water to form N-methyl-hexahydrophthalimide. This imide is then lithiated and coupled via nucleophilic substitution to 2-chloro-4-fluoro-5-nitrophenyl acetate. Reduction of the nitro group using yields the amine intermediate, which undergoes intramolecular cyclisation with the acetate to form the cyclic imide.
| | Metabolic pathway | In the feces and urine of rats, more than 90% of
administered 14C-flumiclorac pentyl is excreted within
48 h of treatment. Flumiclorac pentyl is rapidly and
extensively metabolized. The major fecal metabolites
are identified as the sulfonic acid conjugates, and the
major urinary metabolite is identified as 5-amino-2-
chloro-4-fluorophenoxyacetic acid. The metabolic
reactions include cleavage of the ester linkage, cleavage
of the imide linkage, hydroxylation and following
reduction at the cyclohexene ring of the cyclohexene-
1,2-dicarboxylic acid moiety, and incorporation of a
sulfonic acid group into the carbon ? carbon double bond
of the 3,4,5,6-tetrahydrophthalimide moiety. |
| | FLUMICLORAC-PENTYL Preparation Products And Raw materials |
|