| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:HSD17B13-IN-94
CAS:2848620-90-4
Package:1removed
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| | HSD17B13-IN-94 Basic information |
| Product Name: | HSD17B13-IN-94 | | Synonyms: | HSD17B13-IN-94;4-Thiazolecarboxamide, 5-[(3-chloro-4-hydroxybenzoyl)amino]-N-[2-(2-methoxyphenyl)ethyl]-2-methyl- | | CAS: | 2848620-90-4 | | MF: | C21H20ClN3O4S | | MW: | 445.92 | | EINECS: | | | Product Categories: | | | Mol File: | 2848620-90-4.mol |  |
| | HSD17B13-IN-94 Chemical Properties |
| Boiling point | 611.356±55.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.397±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 6.658±0.20(predicted) |
| | HSD17B13-IN-94 Usage And Synthesis |
| Uses | HSD17B13-IN-94 (Compound 12) is an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for Estradiol (HY-B0141). HSD17B13-IN-94 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD, NASH, or drug-induced liver injury (DILI)[1]. | | References | [1] Joshua Odingo, et al. Thiazole/isothiazole hsd17b13 inhibitors and uses thereof. WIPO (PCT). WO2022216627A1. 2022-10-13 |
| | HSD17B13-IN-94 Preparation Products And Raw materials |
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