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| | N-Boc-dolaproine-amide-Me-Phe Basic information |
| Product Name: | N-Boc-dolaproine-amide-Me-Phe | | Synonyms: | N-Boc-dolaproine-amide-Me-Phe;1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-1-methoxy-2-methyl-3-[[(1S)-1-methyl-2-phenylethyl]amino]-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)- | | CAS: | 3026596-72-2 | | MF: | C23H36N2O4 | | MW: | 404.54 | | EINECS: | | | Product Categories: | | | Mol File: | 3026596-72-2.mol |  |
| | N-Boc-dolaproine-amide-Me-Phe Chemical Properties |
| Boiling point | 552.6±35.0 °C(predicted) | | density | 1.077±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 15.30±0.46(predicted) | | form | Solid | | color | Light yellow to yellow |
| | N-Boc-dolaproine-amide-Me-Phe Usage And Synthesis |
| Uses | N-Boc-dolaproine-amide-Me-Phe is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity[1]. | | References | [1] Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44(5): 937-940. |
| | N-Boc-dolaproine-amide-Me-Phe Preparation Products And Raw materials |
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