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| | Z36-MP5 Basic information |
| Product Name: | Z36-MP5 | | Synonyms: | Z36-MP5;Benzamide, 3-(2,3-dihydro-3-methyl-2-oxo-1H-benzimidazol-5-yl)-N-(5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)- | | CAS: | 2839660-03-4 | | MF: | C22H21N5O2 | | MW: | 387.44 | | EINECS: | | | Product Categories: | | | Mol File: | 2839660-03-4.mol |  |
| | Z36-MP5 Chemical Properties |
| density | 1.417±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 11.928±0.30(predicted) | | form | Solid | | color | White to off-white |
| | Z36-MP5 Usage And Synthesis |
| Uses | Z36-MP5 is an Mi-2β-targeted inhibitor, with IC50 of 0.082 μM. Z36-MP5 can reduce Mi-2β ATPase activity and reactivates ISG transcription. Z36-MP5 can stimulate T-cell-mediated cytotoxicity[1]. | | References | [1] Cang Li, et al. Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation. Nat Commun. 2024 Mar 9;15(1):2163. DOI:10.1038/s41467-024-46422-5 |
| | Z36-MP5 Preparation Products And Raw materials |
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