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| | Antitumor agent-184 Basic information |
| | Antitumor agent-184 Chemical Properties |
| Boiling point | 645.3±65.0 °C(predicted) | | density | 1.52±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 1.20±0.20(predicted) |
| | Antitumor agent-184 Usage And Synthesis |
| Uses | Antitumor agent-184 (compound 12aa) induces cell apoptosis, with the IC50s of 2.35 μM, 7.32 μM and 10.31 μM in B16-F10 cells, 4T1 cells and CT26 cells, respectively[1]. | | References | [1] Irina A Gorbunova, et al. Design and one-pot synthesis of new substituted pyrrolo[1,2-a]thieno[3,2-e]pyrimidine as potential antitumor agents: in vitro and in vivo studies. Bioorg Chem. 2024 Jul:148:107468. DOI:10.1016/j.bioorg.2024.107468 |
| | Antitumor agent-184 Preparation Products And Raw materials |
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