|
|
| | Olean-12-en-28-oic acid, 23-[4-[[5-(3R)-1,2-dithiolan-3-yl-1-oxopentyl]amino]-1-oxobutoxy]-3-oxo-, phenylmethyl ester, (4α)- Basic information |
| | Olean-12-en-28-oic acid, 23-[4-[[5-(3R)-1,2-dithiolan-3-yl-1-oxopentyl]amino]-1-oxobutoxy]-3-oxo-, phenylmethyl ester, (4α)- Chemical Properties |
| Boiling point | 866.4±65.0 °C(predicted) | | density | 1.18±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 16.09±0.46(predicted) |
| | Olean-12-en-28-oic acid, 23-[4-[[5-(3R)-1,2-dithiolan-3-yl-1-oxopentyl]amino]-1-oxobutoxy]-3-oxo-, phenylmethyl ester, (4α)- Usage And Synthesis |
| Uses | Anti-inflammatory agent 65 (compound 29) is a Hederagonic acid derivative with potent anti-inflammatory activity. Anti-inflammatory agent 65 inhibits nitric oxide (NO) release. Anti-inflammatory agent 65 inhibits the nuclear translocation of IRF3 and p65, and disrupts the STING/IRF3/NF-κB signaling pathway, thereby attenuating the inflammatory response[1]. |
| | Olean-12-en-28-oic acid, 23-[4-[[5-(3R)-1,2-dithiolan-3-yl-1-oxopentyl]amino]-1-oxobutoxy]-3-oxo-, phenylmethyl ester, (4α)- Preparation Products And Raw materials |
|