ERK-MYD88 interaction inhibitor 1

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Company Name: Shanghai Chaolan Chemical Technology Center  
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Company Name: Guangzhou Younan Technology Co., Ltd  
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ERK-MYD88 interaction inhibitor 1 Basic information
Product Name:ERK-MYD88 interaction inhibitor 1
Synonyms:ERK-MYD88 interaction inhibitor 1;1H-Benzimidazole-6-carboxamide, 2-[4-(dimethylamino)phenyl]-N-(6-methoxy-3-pyridinyl)-
CAS:2215927-89-0
MF:C22H21N5O2
MW:387.44
EINECS:
Product Categories:
Mol File:2215927-89-0.mol
ERK-MYD88 interaction inhibitor 1 Structure
ERK-MYD88 interaction inhibitor 1 Chemical Properties
density 1.315±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka10.65±0.10(predicted)
form Solid
color White to light yellow
Safety Information
MSDS Information
ERK-MYD88 interaction inhibitor 1 Usage And Synthesis
UsesERK-MYD88 interaction inhibitor 1 is an ERK-MYD88 interaction inhibitor. ERK-MYD88 interaction inhibitor 1 can induce an HRI-mediated integrated stress response (ISR), leading to cancer cell-specific immunogenic cell apoptosis (apoptosis). ERK-MYD88 interaction inhibitor 1 can induce anti-tumor T cell responses in Lewis lung cancer mice, exhibiting anti-tumor activity[1].
References[1] Virard F, et al. Targeting ERK-MYD88 interaction leads to ERK dysregulation and immunogenic cancer cell death. Nat Commun. 2024 Aug 15;15(1):7037. DOI:10.1038/s41467-024-51275-z
ERK-MYD88 interaction inhibitor 1 Preparation Products And Raw materials
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