GA001

GA001 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:GA001
CAS:2097880-27-6
Package:50mg/RMB 13800
GA001 Basic information
Product Name:GA001
Synonyms:GA001;Benzamide, 3-bromo-N-[2-phenyl-1-(3-phenylpropyl)-1H-benzimidazol-5-yl]-
CAS:2097880-27-6
MF:C29H24BrN3O
MW:510.42
EINECS:
Product Categories:
Mol File:2097880-27-6.mol
GA001 Structure
GA001 Chemical Properties
Melting point 220-224 °C
density 1.321±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka12.530±0.43(predicted)
Safety Information
MSDS Information
GA001 Usage And Synthesis
UsesGA001 is a potent G9a antagonist, with an IC50 of 1.32 μM. GA001 induces autophagy and apoptosis that can be used for the breast cancer[1].
References[1] Zhang J, et al. Synthesis and biological evaluation of benzimidazole derivatives as the G9a Histone Methyltransferase inhibitors that induce autophagy and apoptosis of breast cancer cells. Bioorg Chem. 2017 Jun;72:168-181. DOI:10.1016/j.bioorg.2017.04.005
GA001 Preparation Products And Raw materials
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