PROTAC SMARCA2 degrader-15

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PROTAC SMARCA2 degrader-15 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
PROTAC SMARCA2 degrader-15 Basic information
Product Name:PROTAC SMARCA2 degrader-15
Synonyms:PROTAC SMARCA2 degrader-15
CAS:2568276-78-6
MF:C50H61N11O5S
MW:928.16
EINECS:
Product Categories:
Mol File:2568276-78-6.mol
PROTAC SMARCA2 degrader-15 Structure
PROTAC SMARCA2 degrader-15 Chemical Properties
density 1.311±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka6.274±0.30(predicted)
Safety Information
MSDS Information
PROTAC SMARCA2 degrader-15 Usage And Synthesis
UsesSMARCA2 degrader-4 (compound I-332) is a PROTAC degrader targeting SMARCA2; it degrades SMARCA2 proteins in A549 cells with an DC50 <100 nM, and a maximum degradation rate (Dmax%) >90 after 24 h of treatment[1].
References[1] Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. World Intellectual Property Organization, WO2020251971 A1 2020-12-17.
PROTAC SMARCA2 degrader-15 Preparation Products And Raw materials
Tag:PROTAC SMARCA2 degrader-15(2568276-78-6) Related Product Information
dTAGV-1 ARV-766 CC-94676 Acetamide, N-[7-[(3R)-3-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-1-piperidinyl]heptyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- AU-15330 2-Pyrrolidinecarboxamide, 1-[(2S)-2-[4-[4-[[[6-cyclopropyl-4-(1S,4S)-2,5-diazabicyclo[2.2.1]hept-2-yl-7-(6-fluoro-5-methyl-1H-indazol-4-yl)-2-[(tetrahydro-2H-pyran-4-yl)oxy]-8-quinazolinyl]oxy]methyl]phenyl]-1H-1,2,3-triazol-1-yl]-3-methyl-1-oxobutyl]-4-hydroxy-N-[(1R)-2-hydroxy-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (2S,4R)-