PROTAC SMARCA2/4-degrader-7

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PROTAC SMARCA2/4-degrader-7 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
PROTAC SMARCA2/4-degrader-7 Basic information
Product Name:PROTAC SMARCA2/4-degrader-7
Synonyms:PROTAC SMARCA2/4-degrader-7
CAS:2568277-89-2
MF:C51H61N11O5S
MW:940.17
EINECS:
Product Categories:
Mol File:2568277-89-2.mol
PROTAC SMARCA2/4-degrader-7 Structure
PROTAC SMARCA2/4-degrader-7 Chemical Properties
density 1.422±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka6.274±0.30(predicted)
Safety Information
MSDS Information
PROTAC SMARCA2/4-degrader-7 Usage And Synthesis
UsesSMARCA2/4-degrader-7 (compound I-439) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4 proteins in A549 cells with the DC50s <100 nM, and the maximum degradation rate (Dmax%) >90 after 24 h of treatment[1].
References[1] Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. World Intellectual Property Organization, WO2020251971 A1 2020-12-17.
PROTAC SMARCA2/4-degrader-7 Preparation Products And Raw materials
Tag:PROTAC SMARCA2/4-degrader-7(2568277-89-2) Related Product Information
dTAGV-1 CC-94676 AU-15330 ARV-825 ARV-771 dCBP-1