| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Anle138b-F105
CAS:2941386-44-1
Package:10mg;50mg
|
| Company Name: |
Hebei Yaocheng Pharmaceutical Technology Co. Ltd
|
| Tel: |
18033875090 |
| Email: |
yc-eliu@yaochengph.com |
| Products Intro: |
Product Name:3-(3-(benzo[d][1,3]dioxol-5-yl)-1H-pyrazol-5-yl)-N-(2-(2-(2-((3-((4-fluorobenzyl)oxy)benzyl)amino)ethoxy)ethoxy)ethyl)aniline
CAS:2941386-44-1
Purity:95% Package:5g100gkg级
|
|
| | Anle138b-F105 Basic information |
| Product Name: | Anle138b-F105 | | Synonyms: | Anle138b-F105;Benzenemethanamine, N-[2-[2-[2-[[3-[3-(1,3-benzodioxol-5-yl)-1H-pyrazol-5-yl]phenyl]amino]ethoxy]ethoxy]ethyl]-3-[(4-fluorophenyl)methoxy]-;3-(3-(benzo[d][1,3]dioxol-5-yl)-1H-pyrazol-5-yl)-N-(2-(2-(2-((3-((4-fluorobenzyl)oxy)benzyl)amino)ethoxy)ethoxy)ethyl)aniline | | CAS: | 2941386-44-1 | | MF: | C36H37FN4O5 | | MW: | 624.7 | | EINECS: | | | Product Categories: | | | Mol File: | 2941386-44-1.mol |  |
| | Anle138b-F105 Chemical Properties |
| Boiling point | 823.093±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.269±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 12.414±0.10(predicted) |
| | Anle138b-F105 Usage And Synthesis |
| Uses | Anle138b-F105 is an autophagy targeting chimera (AUTOTAC) with DC50 values of 3 nM. Anle138b-F105 targetes tauP301L for lysosomal degradation[1]. | | References | [1] Chang Hoon Ji, et al. The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system. Nat Commun. 2022 Feb 16;13(1):904. DOI:10.1038/s41467-022-28520-4 |
| | Anle138b-F105 Preparation Products And Raw materials |
|