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| Product Name: | S1647 | | Synonyms: | S1647;Benzamide, N-(3,4-dichlorophenyl)-2-[[(3-nitrophenyl)sulfonyl]amino]- | | CAS: | 259528-99-9 | | MF: | C19H13Cl2N3O5S | | MW: | 466.3 | | EINECS: | | | Product Categories: | | | Mol File: | 259528-99-9.mol |  |
| | S1647 Chemical Properties |
| Melting point | 185.0-186.3 °C | | density | 1.591±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 7.174±0.10(predicted) |
| | S1647 Usage And Synthesis |
| Uses | S1647 is a ASBT and SOAT dual inhibitor. S1647 can be used in the study of intrahepatic cholestasis, cholestatic pruritus, and obstipation[1]. | | References | [1] Wannowius M, et al. Structure-Activity Relationships and Target Selectivity of Phenylsulfonylamino-Benzanilide Inhibitors Based on S1647 at the SLC10 Carriers ASBT, NTCP, and SOAT. J Med Chem. 2024 Oct 17. DOI:10.1021/acs.jmedchem.4c01743 |
| | S1647 Preparation Products And Raw materials |
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