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| | Ac-EEVC-OH Basic information |
| Product Name: | Ac-EEVC-OH | | Synonyms: | Ac-EEVC-OH;(2S,5S,8S,11S)-11-Acetamido-8-(3-(tert-butoxy)-3-oxopropyl)-5-isopropyl-16,16-dimethyl-4,7,10,14-tetraoxo-2-(3-ureidopropyl)-15-oxa-3,6,9-triazaheptadecanoic acid;Ac-Glu(OtBu)-Glu(OtBu)-Val-Cit | | CAS: | 2921734-44-1 | | MF: | C31H54N6O11 | | MW: | 686.8 | | EINECS: | | | Product Categories: | | | Mol File: | 2921734-44-1.mol |  |
| | Ac-EEVC-OH Chemical Properties |
| Boiling point | 967.233±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.190±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 3.349±0.10(predicted) | | form | Solid |
| | Ac-EEVC-OH Usage And Synthesis |
| Uses | Ac-EEVC-OH is the linker, that can be used for synthesis of ADC molecule[1]. | | References | [1] Watanabe T, et al., Exo-Cleavable Linkers: Enhanced Stability and Therapeutic Efficacy in Antibody-Drug Conjugates. J Med Chem. 2024 Oct 24;67(20):18124-18138. DOI:10.1021/acs.jmedchem.4c01251 |
| | Ac-EEVC-OH Preparation Products And Raw materials |
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