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| | BIOTIN-11-DUTP Basic information |
| Product Name: | BIOTIN-11-DUTP | | Synonyms: | BIOTIN-11-DUTP;6-[[5-[(3aS,4S,6aR)-2-oxido-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-4-yl]-1-oxidopentylidene]amino]-N-[(E)-3-[4-amino-1-[4-hydroxy-5-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-2-yl]-2-oxido-4H-pyrimidin-5-yl]prop-2-enyl]hexanimidate;BIOTIN-11-DUTP,monolithiummono(((2R,3R,5R)-5-(2,4-dioxo-5-((E)-3-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)prop-1-en-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyltriphosphate) | | CAS: | 1221498-88-9 | | MF: | C28H46LiN6O17P3S | | MW: | 870.62 | | EINECS: | | | Product Categories: | Biotin Derivatives, Labeling and Diagnostics Reagents, Pharmaceuticals, Intermediates & Fine Chemicals;Biotin | | Mol File: | Mol File |  |
| | BIOTIN-11-DUTP Chemical Properties |
| solubility | soluble in water | | Appearance | colorless solid |
| | BIOTIN-11-DUTP Usage And Synthesis |
| Description | Biotinylated deoxyuridine triphosphate (dUTP) can be used for DNA labeling using various methods, including Nick-translation and 3’-terminal non-radioactive labeling. Generated probes can be used in various hybridization experiments such as Southern blot, Northern blot, dot blot, or FISH. Biotin-labeled probes are detected with horseradish peroxidase-conjugated streptavidin or other biomolecule conjugates binding biotin.
«11» in the compound name indicates the length of the linker between dUTP and biotin; this linker increases the efficiency of labeled dUTP incorporation into DNA and interaction of biotin with specific proteins such as avidin/streptavidin or anti-biotin antibodies. | | Uses | Biotin-11-dCTP is a biotin (B389040) labelled nucleotide that is used for non-fluorescent labelling of nucleic acids in purification and detection applications. |
| | BIOTIN-11-DUTP Preparation Products And Raw materials |
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