- 2-FLUORO-4-IODOBENZONITRILE
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- $15.00 / 1KG
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2021-07-13
- CAS:137553-42-5
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- 2-FLUORO-4-IODOBENZONITRILE
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- $15.00 / 1KG
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2021-07-10
- CAS:137553-42-5
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | 2-FLUORO-4-IODOBENZONITRILE Basic information |
| | 2-FLUORO-4-IODOBENZONITRILE Chemical Properties |
| Melting point | 103.7-104.6 | | Boiling point | 264.0±25.0 °C(Predicted) | | density | 1.98±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml | | form | Powder | | color | Red-brown | | Water Solubility | Slightly soluble in water. | | Sensitive | Light Sensitive | | CAS DataBase Reference | 137553-42-5(CAS DataBase Reference) |
| Hazard Codes | T,Xi | | RIDADR | UN3439 | | Hazard Note | Toxic | | HazardClass | IRRITANT, IRRITANT-HARMFUL | | HazardClass | 6.1 | | HS Code | 2926907090 |
| | 2-FLUORO-4-IODOBENZONITRILE Usage And Synthesis |
| Description | 2-Fluoro-4-iodo benzonitrile is a building block. It has been used in the synthesis of L. infantum trypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors. 2-Fluoro-4-iodo benzonitrile has also been used in the synthesis of transient receptor potential ankyrin 1 (TRPA1) antagonists. | | Chemical Properties | Light yellow crystalline | | Uses | Used as pharmaceutical intermediates. | | References | [1] ALEJANDRO REVUELTO. Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase[J]. ACS Infectious Diseases, 2019, 5 6: 873-891. DOI: 10.1021/acsinfecdis.8b00355 [2] KARL S.A. VALLIN . N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptor[J]. Bioorganic & Medicinal Chemistry Letters, 2012, 22 17: Pages 5485-5492. DOI: 10.1016/j.bmcl.2012.07.032 |
| | 2-FLUORO-4-IODOBENZONITRILE Preparation Products And Raw materials |
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