| Company Name: |
Sigma-Aldrich |
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021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
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| | ANTI-CGRP Basic information |
| Product Name: | ANTI-CGRP | | Synonyms: | CALCITONIN GENE RELATED PEPTIDE (CGRP) (AB-1) POLYCLONAL ANTIBODY;Monoclonal Anti-Calcitonin Gene-Related Peptide antibody produced in mouse;Anti-Calcitonin Gene Related Peptide antibody produced in rabbit;ANTI-CALCITONIN GENE RELATED PEPTIDE (AB-1);ANTI-CALCITONIN GENE RELATED PEPTIDE, HUMAN;ANTI-CGRP (AB-1);ANTI-CGRP, HUMAN;ANTI-CGRP | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-CGRP Structure]() |
| | ANTI-CGRP Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution | | biological source | rabbit |
| Hazard Codes | Xn | | Risk Statements | 21/22-22 | | Safety Statements | 36/37 | | WGK Germany | WGK 3 | | Storage Class | 10 - Combustible liquids |
| | ANTI-CGRP Usage And Synthesis |
| Uses | Anti-Calcitonin Gene-Related Peptide (CGRP) antibody is suitable for immunohistochemistry at a working antibody dilution of 1:200 to 1:1000 using formalin-fixed, paraffin-embedded sections or cryostat tissue sections. The antibody may be used for immunofluorescence at a working dilution of 1:500. | | Uses | Anti-Calcitonin Gene Related Peptide antibody produced in rabbit has been used in:
- dot blot immunoassay
- fluorescent labeling
- confocal microscopy
- immunohistofluorescence
- epifluorescence imaging
| | General Description | Calcitonin Gene Related Peptide (CGRP), a cyclic peptide, belongs to a small family of peptides encoded by the calcitonin/CGRP gene complex. The calcitonin/CGRP gene complex consists of at least two genes, encoding for two forms of CGRP: -CGRP (CGRP-I) and -CGRP (CGRP-II). CGRP is synthesized and co-localized with calcitonin in the parafollicular C-cells of the thyroid gland and medullary thyroid carcinoma. It is principally considered a neuropeptide widely distributed in the central and peripheral nervous systems. | | Biochem/physiol Actions | CGRP is thought to act as a neurotransmitter or neuromodulator, particularly in the regulation of autonomic (e.g., cardiovascular, respiratory, gastrointestinal, taste, food intake and sleep) and limbic functions. CGRP is probably involved with substance P in mediating neurogenic inflammation and transmission of pain stimuli via the peripheral nervous system. |
| | ANTI-CGRP Preparation Products And Raw materials |
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