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| | 1,2,9,10-Tetrachlorodecane Basic information |
| Product Name: | 1,2,9,10-Tetrachlorodecane | | Synonyms: | Decane, 1,2,9,10-tetrachloro-;CP-2;1,2,9,10-Tetrachlorodecane | | CAS: | 205646-11-3 | | MF: | C10H18Cl4 | | MW: | 280.06 | | EINECS: | | | Product Categories: | | | Mol File: | 205646-11-3.mol |  |
| | 1,2,9,10-Tetrachlorodecane Chemical Properties |
| Boiling point | 335.7±10.0 °C(Predicted) | | density | 1.167±0.06 g/cm3(Predicted) | | Henry's Law Constant | 5.6×10-2 mol/(m3Pa) at 25℃, Drouillard et al. (1998) |
| | 1,2,9,10-Tetrachlorodecane Usage And Synthesis |
| Biological Activity | 1,2,9,10-Tetrachlorodecane is a cyclic peptide that inhibits the JmjC histone demethylases KDM4 with IC50s of 42 nM and 29 nM for KDM4A and KDM4C, respectively. | | in vitro | 1,2,9,10-Tetrachlorodecane specifically binds to the KDM4A substrate binding pocket. It binds to the KDM4A active site competitively with histone substrates. | | target | | Target | Value | KDM4C
(Cell-free assay) | 29 nM | KDM4A
(Cell-free assay) | 42 nM |
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| | 1,2,9,10-Tetrachlorodecane Preparation Products And Raw materials |
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