N-(3,4-dimethoxyphenyl)ethanamide

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N-(3,4-dimethoxyphenyl)ethanamide Basic information
Product Name:N-(3,4-dimethoxyphenyl)ethanamide
Synonyms:N-(3,4-dimethoxyphenyl)acetamide;N-(3,4-dimethoxyphenyl)ethanamide;2,2-dimethoxy-N-phenylacetamide;Acetamide, N-(3,4-dimethoxyphenyl)-;SKL870;3',4'-DIMETHOXYACETANILIDE;3',4'-DIMETHOXYACETANILIDE
CAS:881-70-9
MF:C10H13NO3
MW:195.22
EINECS:
Product Categories:
Mol File:881-70-9.mol
N-(3,4-dimethoxyphenyl)ethanamide Structure
N-(3,4-dimethoxyphenyl)ethanamide Chemical Properties
Melting point 126-127.7 °C
Boiling point 359.723±32.00 °C(Press: 760.00 Torr)(predicted)
density 1.145±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka14.070±0.70(predicted)
Safety Information
HazardClass IRRITANT
MSDS Information
N-(3,4-dimethoxyphenyl)ethanamide Usage And Synthesis
UsesN-(3,4-Dimethoxyphenyl)acetamide is an intermediate used in the synthesis of 5,6-Orthoquinone Primaquine-d6 Hydrobromide (O697512), which is an isotope labeled compound of 5,6-Orthoquinone Primaquine (O697510). 5,6-Orthoquinone Primaquine is used in the study of the differential pharmacological and toxicological properties of primaquine enantiomers. Primaquine is currently the only approved drug for the treatment and radical cure of Plasmodium vivax malaria.
Synthesis Reference(s)The Journal of Organic Chemistry, 59, p. 5814, 1994 DOI: 10.1021/jo00098a050
N-(3,4-dimethoxyphenyl)ethanamide Preparation Products And Raw materials
Preparation Products3,4-Dimethoxyphenol-->2'-Amino-4',5'-dimethoxyacetophenone-->6,7-DiMethoxy-2-oxo-1,2-dihydro-quinoline-3-carbaldehyde
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