Ethane, 1,2-bis(2-bromoethoxy)- manufacturers
- Br-PEG2-Br
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2025-06-07
- CAS:31255-10-4
- Min. Order: 10g
- Purity: >98.00%
- Supply Ability: 10g
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| | Ethane, 1,2-bis(2-bromoethoxy)- Basic information |
| Product Name: | Ethane, 1,2-bis(2-bromoethoxy)- | | Synonyms: | Bromo-PEG2-bromide;Br-PEG2-bromide;Ethane, 1,2-bis(2-bromoethoxy)-;Bromo-PEG3-bromide;CAS_31255-10-4;1-bromo-2-[2-(2-bromoethoxy)ethoxy]ethane;Br-PEG2-CH2CH2Br;1,2-Bis(2-bromoethoxy)ethane | | CAS: | 31255-10-4 | | MF: | C6H12Br2O2 | | MW: | 275.97 | | EINECS: | | | Product Categories: | | | Mol File: | 31255-10-4.mol |  |
| | Ethane, 1,2-bis(2-bromoethoxy)- Chemical Properties |
| Boiling point | 140 °C(Press: 12 Torr) | | density | 1.6777 g/cm3 | | storage temp. | -20°C Freezer, Under inert atmosphere | | solubility | Chloroform, Ethyl Acetate (Slightly) | | form | Oil | | color | Colourless | | Stability: | Moisture Sensitive | | InChI | InChI=1S/C6H12Br2O2/c7-1-3-9-5-6-10-4-2-8/h1-6H2 | | InChIKey | UOWNEWCMPHICQH-UHFFFAOYSA-N | | SMILES | C(OCCBr)COCCBr |
| | Ethane, 1,2-bis(2-bromoethoxy)- Usage And Synthesis |
| Description | Bromo-PEG2-bromide is a PEG linker containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | Bromo-PEG2-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] Chen TH, et al. Metal-organic frameworks constructed from crown ether-based 1,4-benzenedicarboxylic acid derivatives. Dalton Trans. 2016 Feb 21;45(7):3063-9. DOI:10.1039/c5dt04316f |
| | Ethane, 1,2-bis(2-bromoethoxy)- Preparation Products And Raw materials |
| Raw materials | Thionyl bromide-->1-Bromo-2-chloromethoxy-ethane-->Triethylene Glycol Dimethanesulfonate-->Tri(Ethylene Glycol) DI-P-Toluenesulfonate-->Ethylene-->1,4-Dioxane-->Triethylene glycol | | Preparation Products | 1,8-Diamino-3,6-dioxaoctane-->2-[2-(2-Azidoethoxy)ethoxy]ethanamine-->2,2'-Dibromodiethyl ether-->3,6-Dioxa-1,8-octanedithiol-->Ethanamine, 2,2-1,2-ethanediylbis(oxy)bisN,N-dimethyl- |
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