1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate

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1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate manufacturers

  • SGS518 oxalate
  • SGS518 oxalate pictures
  • 2026-07-03
  • CAS:445441-27-0
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 20Tons
  • SGS518 oxalate
  • SGS518 oxalate pictures
  • $2500.00
  • 2026-05-11
  • CAS:445441-27-0
  • Purity:
  • Supply Ability: 10g
1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate Basic information
Product Name:1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate
Synonyms:1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate;SGS 518 oxalate;SGS518 oxalate,SGS-518 oxalate;1-methyl-3-(1-methylpiperidin-4-yl)-1H-indol-5-yl 2,6-difluorobenzenesulfonate oxalate;Benzenesulfonic acid, 2,6-difluoro-, 1-methyl-3-(1-methyl-4-piperidinyl)-1H-indol-5-yl ester, ethanedioate (1:1)
CAS:445441-27-0
MF:C23H24F2N2O7S
MW:510.51
EINECS:
Product Categories:
Mol File:445441-27-0.mol
1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate Structure
1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate Chemical Properties
storage temp. Desiccate at RT
solubility Soluble to 100 mM in DMSO
form Powder
Safety Information
MSDS Information
1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate Usage And Synthesis
UsesSGS 518 Oxalate is a 5-HT6 antgaonist.
in vivo

SGS518 oxalate (30 mg/kg; i.p. for 30 min) protects Abca4–/–Rdh8 sup>–/– mouse retinas from light-induced damage[1].

Animal Model:Abca4–/–Rdh8 sup>–/–mice are exposed at white light[1]
Dosage:30 mg/kg
Administration:I.p. injection for 30 minutes
Result:A marked preservation of the photoreceptor layer.
Reduced formation of autofluorescent spots in mice.
Protected retinal morphology.
IC 505-HT6 Receptor
1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate Preparation Products And Raw materials
Tag:1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate(445441-27-0) Related Product Information
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