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| | GSK369796 Basic information |
| Product Name: | GSK369796 | | Synonyms: | GSK369796;GSK369796 Dihydrochloride;Phenol, 5-[(7-chloro-4-quinolinyl)amino]-2-[[(1,1-dimethylethyl)amino]methyl]-, hydrochloride;GSK 369796; GSK-369796;N-tert-butylisoquine;CS-2373;GSK369796 (GSK-369796, GSK 369796);GSK369796 HCL | | CAS: | 1010411-21-8 | | MF: | C20H24Cl3N3O | | MW: | 428.78306 | | EINECS: | | | Product Categories: | | | Mol File: | 1010411-21-8.mol |  |
| | GSK369796 Chemical Properties |
| storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO:100.0(Max Conc. mg/mL);233.22(Max Conc. mM) Water:50.0(Max Conc. mg/mL);116.61(Max Conc. mM) | | form | A solid | | color | Light yellow to yellow |
| | GSK369796 Usage And Synthesis |
| Uses | 5-[(7-Chloro-4-quinolinyl)amino]-2-[[(1,1-dimethylethyl)amino]methyl]phenol Hydrochloride is an effective aminoquinoline antimalarial. | | in vivo | In vivo, GSK369796 Dihydrochloride can inhibit the growth of Plasmodium berghei ANKA with ED50 and ED90 of 2.8 and 4.7 mg/kg, respectively[1]. | | IC 50 | Plasmodium |
| | GSK369796 Preparation Products And Raw materials |
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