Cyclobutanol, 3-amino-, hydrochloride (1:1), cis- manufacturers
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| | Cyclobutanol, 3-amino-, hydrochloride (1:1), cis- Basic information |
| Product Name: | Cyclobutanol, 3-amino-, hydrochloride (1:1), cis- | | Synonyms: | cis-3-Aminocyclobutanol hydrochloride - A0711;CIS-3-AMINOCYCLOBUTANOL HCL;cis-3-AMinocyclobutanol hydrochloride;Cyclobutanol, 3-aMino-, hydrochloride, cis-;Cyclobutanol, 3-amino-, hydrochloride (1:1),cis-;cis-3-Aminocyclobutan-1-ol hydrochloride;3-aminocyclobutan-1-ol hydrochloride, cis;(1S,3S)-3-aminocyclobutanol hydrochloride | | CAS: | 1219019-22-3 | | MF: | C4H9NO.ClH | | MW: | 123.58 | | EINECS: | | | Product Categories: | | | Mol File: | 1219019-22-3.mol |  |
| | Cyclobutanol, 3-amino-, hydrochloride (1:1), cis- Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | powder | | color | White | | InChI | InChI=1/C4H9NO.ClH/c5-3-1-4(6)2-3;/h3-4,6H,1-2,5H2;1H/t3-,4+; | | InChIKey | XUMSHCRPQCZRGX-HKTIBRIUNA-N | | SMILES | N[C@@H]1C[C@H](O)C1.Cl |&1:1,3,r| |
| | Cyclobutanol, 3-amino-, hydrochloride (1:1), cis- Usage And Synthesis |
| Synthesis | General procedure for the synthesis of cis-3-aminocyclobutanol hydrochloride from tert-butyl (cis-3-hydroxycyclobutyl)carbamate: tert-butyl (1S,3S)-3-hydroxycyclobutylcarbamate (see Preparation 4A; 187 mg, 1 mmol, 1.0 equiv.) was dissolved in 4N HCl/MeOH solution (15 mL), and the reaction was stirred for 4 hours at room temperature. Upon completion of the reaction, the reaction mixture was concentrated to afford (1S,3S)-3-aminocyclobutanol hydrochloride (120 mg, 0.98 mmol, 98% yield).ESI-MS (M+1): 88 (calculated value C4H9NO: 87). | | References | [1] Patent: WO2011/143366, 2011, A1. Location in patent: Page/Page column 144 |
| | Cyclobutanol, 3-amino-, hydrochloride (1:1), cis- Preparation Products And Raw materials |
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