|
|
| | trans-trismethoxy Resveratrol-d4 Basic information |
| | trans-trismethoxy Resveratrol-d4 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 50 mg/ml,DMSO: 50 mg/ml,DMSO:PBS(pH 7.2) (1:2): 0.25 mg/ml,Ethanol: 10 mg/ml |
| | trans-trismethoxy Resveratrol-d4 Usage And Synthesis |
| Description | trans-trismethoxy Resveratrol-d4 is intended for use as an internal standard for the quantification of trans-trismethoxy resveratrol by GC- or LC-MS. trans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities. It is cytotoxic to several cancer cell lines, including PC3, KB, HT-29, SW480, and HL-60 cells (IC50s =3.6, 10.2, 16.1, 54, and 2.5 μM, respectively). trans-trismethoxy Resveratrol (15 μM) inhibits TNF-α-induced activation of NF-κB in HEK293T cells in a reporter assay. It inhibits angiogenesis in zebrafish embryos when used at a concentration of 0.1 μM. | | Uses | trans-Trismethoxy Resveratrol-d4 is the deuterium labeled trans-Trismethoxy Resveratrol[1]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110 |
| | trans-trismethoxy Resveratrol-d4 Preparation Products And Raw materials |
|