1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal

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1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Suppliers list
Company Name: Creative Enzymes
Tel: 1-516-855-7709
Email: info@creative-enzymes.com
Products Intro: Product Name:16:0 PEG350 PE
CAS:474922-84-4
Purity:>99%
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
Tel: +undefined18143011203
Email: info@chemextension.com
Products Intro: Product Name:16:0 PEG PE, MW 350
CAS:474922-84-4
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Shanghai T&W Pharmaceutical Co., Ltd.  
Tel: +86 21 61551611
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Products Intro: Product Name:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (ammonium sal
CAS:474922-84-4
Purity:98% Package:50kg;25kg;10kg;5kg;500g;500mg;
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Products Intro: Product Name:16:0 PEG5000 PE
CAS:474922-84-4
Purity:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy( Package:500MG Remarks:880200P-500MG
Company Name: Shochem(Shanghai)Co.,Ltd  
Tel: +86-021-51783479 +86-13816874662
Email: info@shochem.com
Products Intro: Product Name:DPPE-MPEG2000
CAS:474922-84-4
Purity:98% Package:1g/;10g/;100g/
1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Basic information
Product Name:1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal
Synonyms:DipalmitoylphosphatidylethanolamineN-[methoxy(polyethylene glycol)-2000];1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal;alpha-[(9R)-6-Hydroxy-6-oxido-1,12-dioxo-9-[(1-oxohexadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphaheptacos-1-yl]-omega-methoxypoly(oxy-1,2-ethanediyl) ammonium salt;16:0 PEG3000 PE;16:0 PEG5000 PE;16:0 PEG2000 PE;16:0 PEG1000 PE;16:0 PEG PE, MW 350
CAS:474922-84-4
MF:(C2H4O)nC39H76NO10P.H3N
MW:0
EINECS:
Product Categories:
Mol File:474922-84-4.mol
1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Structure
1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Chemical Properties
storage temp. -20°C
solubility Chloroform: soluble
form Solid
color White to off-white
InChIKeyAEGGEICNCATQIE-VDKVIGKMSA-N
SMILES[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Usage And Synthesis
Description16:0 PEG PE, MW 1,100 is a PEG-modified phospholipid conjugate used in liposome formation of sterically stabilized liposomes with low reticuloendothelial system uptake and increased circulation duration to target cells.
Uses16:0 PEG5000 PE or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 has been used in preparation of lipid bilayer. It has also been used in liposome preparation.
Uses16:0 PEG2000 PE, or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] has been used in liposome preparation. It has also been used in preparation of tripeptide arginine-glycine-aspartic acid magnetoliposomes (RGD-MLPs) and poly(ethylene glycol) (PEG)- MLPs.
Uses16:0 PEG3000 PE is suitable for the preparation of liposome and advanced drug delivery nano liposomal system.
General Description16:0 PEG5000 PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 (DPPE-PEG 5000), is a mPEG phospholipid conjugate. Poly(ethylene glycol) (PEG)-based liposomal formulations are widely used in preparation of biocompatible self-assembled drug-delivery systems. These systems have an ability to escape the recognition and uptake by cells in the immune system at the same time it extends the residence time of the liposomes and allows continuous drug release into the targeted cells.
Biochem/physiol ActionsPolyethylene glycol (PEG) conjugated phospholipids are useful in liposome formulation for maintaining their stereochemistry. They also serve as drug carriers. PEGylated lipids aid in the formation of mixed micelles at high concentration.
References[1] BRETT A HOWELL  Anuj C. Bupivacaine binding to pegylated liposomes.[J]. Anesthesia and analgesia, 2009, 109 2: 678-682. DOI: 10.1213/ane.0b013e3181a8da61
[2] BRETT A. HOWELL  Anuj C. Binding of Imipramine, Dosulepin, and Opipramol to Liposomes for Overdose Treatment[J]. Journal of pharmaceutical sciences, 2009, 98 10: Pages 3718-3729. DOI: 10.1002/jps.21683
1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Preparation Products And Raw materials
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