N-ethylpyridin-3-amine manufacturers
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| | N-ethylpyridin-3-amine Basic information |
| | N-ethylpyridin-3-amine Chemical Properties |
| Boiling point | 229.2±13.0 °C(Predicted) | | density | 1.029±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, protect from light | | pka | 6.54±0.11(Predicted) | | Appearance | White to yellow Solid-Liquid Mixture |
| | N-ethylpyridin-3-amine Usage And Synthesis |
| Synthesis | GENERAL STEPS: 3-Aminopyridine (2.0 g, 21.2 mmol), acetonitrile (4.36 g, 106 mmol) and 10% Pd/C catalyst (0.2 g) were dissolved in methanol (20 mL). The reaction mixture was stirred at 25°C under hydrogen atmosphere for 16 hours. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure. The crude product was purified by silica gel column chromatography using 5-10% methanol/dichloromethane as eluent to afford N-ethylpyridin-3-amine (0.7 g). | | References | [1] Organic Letters, 2004, vol. 6, # 26, p. 4977 - 4980
[2] Organic and Biomolecular Chemistry, 2012, vol. 10, # 2, p. 293 - 304
[3] Patent: US2016/96835, 2016, A1. Location in patent: Paragraph 0088; 0089 |
| | N-ethylpyridin-3-amine Preparation Products And Raw materials |
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