AMG 837 (sodiuM salt)

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AMG 837 (sodiuM salt) Basic information
Product Name:AMG 837 (sodiuM salt)
Synonyms:AMG 837 (sodiuM salt);AMG-837 Sodium
CAS:865231-45-4
MF:C26H22F3NaO3
MW:462.44
EINECS:
Product Categories:
Mol File:865231-45-4.mol
AMG 837 (sodiuM salt) Structure
AMG 837 (sodiuM salt) Chemical Properties
storage temp. Store at -20°C
solubility Soluble in DMSO
Safety Information
MSDS Information
AMG 837 (sodiuM salt) Usage And Synthesis
UsesAMG 837 (sodium salt) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
References[1] Lin DC, et al. AMG 837: a novel GPR40/FFA1 agonist that enhances insulin secretion and lowers glucose levels in rodents. PLoS One. 2011;6(11):e27270. DOI:10.1371/journal.pone.0027270
[2] Houze JB, et al. AMG 837: a potent, orally bioavailable GPR40 agonist. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1267-70. DOI:10.1016/j.bmcl.2011.10.118
AMG 837 (sodiuM salt) Preparation Products And Raw materials
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