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ChemPep, Inc. |
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MPEG5-Hydrazide manufacturers
- m-PEG6-Hydrazide
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2025-06-07
- CAS:1449390-64-0
- Min. Order: 250mg
- Purity: >98.00%
- Supply Ability: 250mg
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| | MPEG5-Hydrazide Basic information |
| | MPEG5-Hydrazide Chemical Properties |
| Boiling point | 478.5±45.0 °C(Predicted) | | density | 1.100±0.06 g/cm3(Predicted) | | pka | 12.82±0.35(Predicted) |
| | MPEG5-Hydrazide Usage And Synthesis |
| Uses | m-PEG6-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | m-PEG6-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | MPEG5-Hydrazide Preparation Products And Raw materials |
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Tag:MPEG5-Hydrazide(1449390-64-0)
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