ChemicalBook > Product Catalog >Catalyst and Auxiliary >Polyethylene glycol derivatives >1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt)

1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt)

1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt) Suppliers list
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Products Intro: Product Name:DSPE-PEG-Biotin
CAS:385437-57-0
Purity:96%+ Package:0.1g, 0.5g,1g, 5g,25g 100g Remarks:Monodisperse long-chain PEG,pls search keyword to find your prodcut in our web site.
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Products Intro: CAS:385437-57-0
Purity:95%min Package:5g;25g;100g;500g;1kg;25kg
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Products Intro: Product Name:DSPE-PEG(2000) Biotin
CAS:385437-57-0
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Products Intro: Product Name:1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt)
CAS:385437-57-0
Purity:99.00% Package:25kgs/Drum;200kgs/Drum Remarks:ISO 9001:2015 REACH Approved Manufacturer
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Products Intro: Product Name:DSPE-PEG-Biotin, MW 2,000
CAS:385437-57-0
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt) Basic information
Product Name:1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt)
Synonyms:1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt);DSPE-PEG(2000) Biotin;1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-[BIOTINYL(POLYETHYLENE GLYCOL)-2000] (AMMONIUM SALT);DSPE-PEG(2000) BIOTIN;DSPE-PEG-2K-Biotin;1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt) ISO 9001:2015 REACH;DSPE-PEG-Biotin (MW 2000);DSPE-MPEG-2000-Biotin;DSPEPEGBiotin (MW 2000),DSPE PEG Biotin (MW 2000)
CAS:385437-57-0
MF:(C2H4O)nC54H101N4O12PS.Na
MW:0
EINECS:
Product Categories:peg
Mol File:385437-57-0.mol
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt) Structure
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt) Chemical Properties
storage temp. -20°C
solubility Ethanol: Soluble: =10 mg/ml
form Solid
color White to off-white
Safety Information
WGK Germany WGK 3
Hazard ClassificationsAcute Tox. 3 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 3
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1
STOT SE 3
MSDS Information
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt) Usage And Synthesis
DescriptionDSPE-PEG-Biotin, MW 2,000 is a biotin amphipilic material which forms micelles in an aqueous solution and binds selectively with streptavidin and avidin. This polymer is very promising nanocarriers for therapeutic drug delivery, imaging and molecular labeling.
UsesDSPE-PEG-Biotin, MW 1000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
[2] ZHANG J, LUO Y, ZHAO X, et al. Co-delivery of doxorubicin and the traditional Chinese medicine quercetin using biotin–PEG2000–DSPE modified liposomes for the treatment of multidrug resistant breast cancer[J]. RSC Advances, 2016, 114: 113173-113184. DOI: 10.1039/c6ra24173e
[3] DONGHUA LIU. Tumor Specific Delivery and Therapy by Double-Targeted Nanostructured Lipid Carriers with Anti-VEGFR-2 Antibody[J]. Molecular Pharmaceutics, 2011, 8 6: 2291-2301. DOI: 10.1021/mp200402e
[4] JAKOB WALLNER. An approach for liposome immobilization using sterically stabilized micelles (SSMs) as a precursor for bio-layer interferometry-based interaction studies[J]. Colloids and Surfaces B: Biointerfaces, 2017, 154: Pages 186-194. DOI: 10.1016/j.colsurfb.2017.03.015
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt) Preparation Products And Raw materials
Tag:1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt)(385437-57-0) Related Product Information
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