| Company Name: |
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
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| Tel: |
17702719238 18971495150; |
| Email: |
sales@sun-shinechem.com |
| Products Intro: |
Product Name:EX-527(R)
CAS:848193-69-1
Purity:98% HPLC Package:50.0mg;100.0mg; 200.0mg;500mg;1g;5g; 10g
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| Company Name: |
Haoyuan Chemexpress Co., Ltd.
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| Tel: |
021-58950125 |
| Email: |
info@chemexpress.com |
| Products Intro: |
Product Name:EX-527 (R-enantiomer)
CAS:848193-69-1
Purity:>98% Package:2333RMB/2mg
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| Company Name: |
MedChemexpress LLC
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| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:EX-527 (R-enantiomer)
CAS:848193-69-1
Purity:>98% Package:2333RMB/2mg
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| Company Name: |
ShangHai Caerulum Pharma Discovery Co., Ltd.
|
| Tel: |
18149758185 18149758185 |
| Email: |
sales-cpd@caerulumpharma.com |
| Products Intro: |
Product Name:EX-527 (R-enantioMer)
CAS:848193-69-1
Purity:98% Package:10mg;100mg;1g;10g;100g;1kg
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EX-527 (R-enantioMer) manufacturers
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| | EX-527 (R-enantioMer) Basic information |
| Product Name: | EX-527 (R-enantioMer) | | Synonyms: | EX-527 (R-enantioMer);(R)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide;EX-527(R‰;(R)-Selisistat;(R)-SELISISTAT; EX-527(R); EX 527(R); EX527(R);;Sirtuin,Selisistat R enantiomer,inhibit,Selisistat Renantiomer,Inhibitor,(R)-Selisistat;1H-Carbazole-1-carboxamide, 6-chloro-2,3,4,9-tetrahydro-, (1R)-;Selisistat R-enantiomer, 10 mM in DMSO | | CAS: | 848193-69-1 | | MF: | C13H13ClN2O | | MW: | 248.71 | | EINECS: | | | Product Categories: | | | Mol File: | 848193-69-1.mol |  |
| | EX-527 (R-enantioMer) Chemical Properties |
| Boiling point | 531.7±38.0 °C(Predicted) | | density | 1.388±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Powder | | pka | 16.12±0.40(Predicted) | | color | Light yellow to yellow |
| | EX-527 (R-enantioMer) Usage And Synthesis |
| Uses | (R)-Selisistat ((R)-EX-527) is a R-enantiomer of Selisistat. Selisistat (EX-527) is a potent and selective SIRT1 inhibitor with IC50 of 98 nM. | | Definition | ChEBI: (R)-selisistat is a 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide that has R configuration. It is the inactive enantiomer. It is an enantiomer of a (S)-selisistat. | | References | [1] Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54. DOI:10.1021/jm050522v |
| | EX-527 (R-enantioMer) Preparation Products And Raw materials |
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