ORM-12741 manufacturers
- ORM-10921
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- $397.00
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2026-05-11
- CAS:610782-82-6
- Purity: 99.98%
- Supply Ability: 10g
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| | ORM-12741 Basic information |
| Product Name: | ORM-12741 | | Synonyms: | ORM-12741;ORM 10921;ORM-10921;ORM 10921,ORM10921;2H-Benzofuro[2,3-a]quinolizine, 1,3,4,6,7,12b-hexahydro-1-(methoxymethyl)-1-methyl-, (1S,12bS)-;ORM10921 | | CAS: | 610782-82-6 | | MF: | C18H23NO2 | | MW: | 285.38 | | EINECS: | | | Product Categories: | | | Mol File: | 610782-82-6.mol |  |
| | ORM-12741 Chemical Properties |
| Boiling point | 384.0±32.0 °C(Predicted) | | density | 1.16±0.1 g/cm3(Predicted) | | form | Solid | | pka | 7.70±0.40(Predicted) | | color | Light yellow to yellow |
| | ORM-12741 Usage And Synthesis |
| Uses | ORM-10921 free base is a selective α-2C adrenergic receptor antagonist with a Ki of 1.4 nM. ORM-10921 free base displays potent antidepressant and antipsychotic-like effects[1]. | | IC 50 | Alpha-2C adrenergic receptor: 1.4 nM (Ki) | | References | [1] Jukka Sallinen, et al. Pharmacological characterisation of a structurally novel α2C-adrenoceptor antagonist ORM-10921 and its effects in neuropsychiatric models. Basic Clin Pharmacol Toxicol. 2013 Oct;113(4):239-49. DOI:10.1111/bcpt.12090 |
| | ORM-12741 Preparation Products And Raw materials |
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