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2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-

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2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Suppliers list
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
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Products Intro: Product Name:2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-
CAS:21416-87-5
Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer
Company Name: LGM Pharma  
Tel: 1-(800)-881-8210
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Products Intro: Product Name:Razoxane
CAS:21416-87-5
Purity:Typically NLT 98%
Company Name: Shaanxi Dideu Medichem Co. Ltd  
Tel: 029-81154043 17391733319
Email: 1086@dideu.com
Products Intro: Product Name:Razoxane
CAS:21416-87-5
Purity:98% Package:25千克/桶
Company Name: Beijing Boorsen Biotechnology Co., Ltd  
Tel: 400-901-9800 18611424007
Email: cis@bioss.com.cn
Products Intro: Product Name:Razoxane
Purity:0.9942 Package:1mg;5mg Remarks:D54010
Company Name: Venkat Pharma  
Tel: 08048372463Ext 224
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Products Intro: Product Name:Zinecard
CAS:21416-87-5

2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- manufacturers
2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Basic information
Product Name:2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-
Synonyms:2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-;(±)-1，2-Bis(3，5-diox-opiperazinyl)propane;Razoxane;ICRF;ICRF-159;Eucardion;ICI-59118;ICRF-187
CAS:21416-87-5
MF:C11H16N4O4
MW:268.27
EINECS:
Product Categories:
Mol File:21416-87-5.mol
2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Structure
2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Chemical Properties
Melting point 233.5°C
Boiling point 411.43°C (rough estimate)
density 1.2576 (rough estimate)
refractive index 1.6081 (estimate)
storage temp. Refrigerator
solubility DMSO (Slightly)
form Solid
color White
Safety Information
MSDS Information
2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Usage And Synthesis
Chemical PropertiesWhite or almost white or light beige crystal or crystalline powder, odorless, slightly bitter taste. Soluble in hot water, insoluble in water or ethanol. Melting point 233-234℃(decomposition), melting point 237-239℃. (+)-configuration (Dexrazoxane): [24584-09-6]. Crystallized from aqueous methanol-ether, melting point 193 °C. [α]D+11.35° (C=5, dimethylformamide). Solubility (mg/ml): 10-12 (water), 35-43 (0.1 mol/L hydrochloric acid), 25-34 (0.1 mol/L sodium hydroxide), 6.7-10 (10% ethanol), 1 (methanol), 7.1-10 [water-dimethylformamide (1:1)], 9.7-14.5 [0.1 mol/L citrate buffer (Ph 4) ], 8.7 to 13 [0.1 mol/L boric acid buffer (Ph 9)].
UsesRazoxane is an inhibitor of Topo II.
DefinitionChEBI: Razoxane is a N-alkylpiperazine.
Safety ProfileSuspected carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by intraperitoneal route. Experimental teratogenic and reproductive effects. Human systemic effects by ingestion: nausea, thrombocytopenia, leukopenia. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Preparation Products And Raw materials
Raw materialsFormamide-->1,2-Diaminopropane-N,N,N',N'-tetraacetic acid
Tag:2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-(21416-87-5) Related Product Information
Dexrazoxane Pemetrexed Disodium (S)-(-)-1,2-Diaminopropane dihydrochloride Dexrazoxane hydrochloride 4-(2-AMINO-ETHYL)-PIPERAZIN-2-ONE 1,1'-ethylenedipiperazine 4,4-(2,3-BUTANEDIYL)-BIS(2,6-PIPERAZINEDIONE) ETHYLIMINUM 4-methylpiperazine-2,6-dione 1-(2-DIETHYLAMINOETHYL)PIPERAZINE 2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS- Piperazine-2,6-dione