8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER manufacturers
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| | 8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER Basic information |
| Product Name: | 8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER | | Synonyms: | NOHLKSJQMSPOTB-YRLDPNHWSA-N;8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER;9-OXO-11ALPHA,15S-DIHYDROXY-(8BETA)-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER;Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, 1-methylethyl ester, (5Z,8β,13E,15S)- | | CAS: | 330589-21-4 | | MF: | C23H38O5 | | MW: | 394.55 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER Chemical Properties |
| Boiling point | 511.8±50.0 °C(Predicted) | | density | 1.079±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: >30 mg/ml (from PGF2a isopropy; DMSO: >50 mg/ml (from PGF2a isopropy; Ethanol: >50 mg/ml (from PGF2a isopropy; PBS pH 7.2: <50 μg/ml (from PGF2a isopropy | | pka | 13.79±0.60(Predicted) |
| | 8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER Usage And Synthesis |
| Description | 8-iso PGE2 isopropyl ester is a more lipophilic form of the free acid, 8-iso PGE2. Prostaglandin esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of prostaglandins show greatly diminished agonist activity in vitro compared to the parent free acids. | | Uses | 8-Iso prostaglandin E2 isopropyl ester is a more lipophilic form of the free acid, 8-iso Prostaglandin E2. |
| | 8-ISO PROSTAGLANDIN E2 ISOPROPYL ESTER Preparation Products And Raw materials |
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