升压素
| 中文名称 | 升压素 |
|---|---|
| 中文同义词 | 运动升压素;升压素;KINETENSIN,神经降压素样肽;[K118986] KINETENSIN TFA盐,神经降压素样肽;激肽释放酶原激活肽;化合物 Kinetensin;NAP1L1 多克隆抗体-E-AB-10482;重组人 OPTN蛋白 (His标签)-PDEH101085 |
| 英文名称 | KINETENSIN |
| 英文同义词 | KINETENSIN;KINETENSIN (HUMAN);Kinetensin, ≥97% (HPLC);IARRHPYFL;ILE-ALA-ARG-ARG-HIS-PRO-TYR-PHE-LEU;H-ILE-ALA-ARG-ARG-HIS-PRO-TYR-PHE-LEU-OH;NEUROTENSIN-RELATED PEPTIDE;NRP |
| CAS号 | 103131-69-7 |
| 分子式 | C56H85N17O11 |
| 分子量 | 1172.38 |
| EINECS号 | |
| 相关类别 | 细胞信号和神经生物学;多肽;细胞生物学;标准品;Peptide;Neuropeptides;Neurotensins;Peptides for Cell Biology;Neuromedins and related |
| Mol文件 | 103131-69-7.mol |
| 结构式 |  |
升压素 性质
| 储存条件 | 2-8°C |
|---|---|
| 溶解度 | TFA 0.1%：1 mg/mL，澄清，无色 |
| 形态 | 粉末 |
| 颜色 | 白色至米白色 |
| 水溶解性 | Soluble to 2 mg/ml in water |
| 序列 | Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu |
Neurotensin Receptor
The peptide kinetensin isolated from pepsin-treated human plasma induces a dose-dependent release of histamine when exposed to rat peritoneal mast cells. The threshold concentration is around 1 μM, the ED 50 is 10 μM, and the optimal concentration of between 100 to 1000 μM released 80% of the total histamine. Kinetensin is 10 to 100 times less potent than neurotensin and equipotent with the opioid peptide dynorphin. The histamine release is clearly temperature-dependent, with no release occurring at 0 or 45 °C and with an optimum around 37 °C. The histamine release is significantly reduced in the absence of extracellular calcium.
Kinetensin also induces a dose-dependent increase in vascular permeability when injected intradermally into rats.
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英文
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-P1255 | 升压素 Kinetensin | 103131-69-7 | 1mg | 918元 |
| 2025/12/22 | HY-P1255 | 升压素 Kinetensin | 103131-69-7 | 5mg | 1830元 |