- HDAC-IN-3
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- $40.00 / 1mg
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2025-10-13
- CAS:1018673-42-1
- Min. Order:
- Purity: 99.62%
- Supply Ability: 10g
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| | cyclopentyl 2-cyclohexyl-2-((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)methylamino)acetate Basic information |
| | cyclopentyl 2-cyclohexyl-2-((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)methylamino)acetate Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO:81.0(Max Conc. mg/mL);200.73(Max Conc. mM)
Ethanol:15.0(Max Conc. mg/mL);37.17(Max Conc. mM) | | form | A crystalline solid | | color | Light yellow to khaki |
| | cyclopentyl 2-cyclohexyl-2-((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)methylamino)acetate Usage And Synthesis |
| Description | GSK3117391 is a histone deacetylase (HDAC) inhibitor (IC50 = <100 nM in HeLa nuclear extracts). It inhibits growth of U937 and HUT cancer cells (IC50s = <330 nM). | | Uses | GSK3117391 (ESM-HDAC391) is a histone deacetylase (HDAC) inhibitor, extracted from patent WO/2008040934 A1.
Target: HDAC | | IC 50 | HDAC | | References | [1] Davidson Alan Hornsby, et al. Preparation of amino acid-based hydroxamic acids as histone deacetylase (HDAC) inhibitors. From PCT Int. Appl. (2008), WO 2008040934 A1 20080410. |
| | cyclopentyl 2-cyclohexyl-2-((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)methylamino)acetate Preparation Products And Raw materials |
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