| Company Name: |
TCI Europe |
| Tel: |
320-37350700 |
| Email: |
sales@tcieurope.eu |
| Company Name: |
TCI AMERICA |
| Tel: |
800-4238616 |
| Email: |
sales@tciamerica.com |
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| | S-Acetyl-PEG3-Azido Basic information |
| Product Name: | S-Acetyl-PEG3-Azido | | Synonyms: | AZIDO-PEG3-THIOACETATE;S-Acetyl-PEG3-Azido;S-acetyl-dPEG4-azido;S-Acetyl-PEG3-azide;S-Acetyl-PEG3-N3;Acetylthio-PEG3-C2-Azide;Ethanethioic Acid S-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl] Ester;S-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl] Ethanethioate | | CAS: | 1310827-26-9 | | MF: | C10H19N3O4S | | MW: | 277.34 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1310827-26-9.mol |  |
| | S-Acetyl-PEG3-Azido Chemical Properties |
| form | clear liquid | | color | Light yellow to Brown |
| | S-Acetyl-PEG3-Azido Usage And Synthesis |
| Description | S-Acetyl-PEG3-azide is a PEG linker containing an azide group and a sulfur acetyl group. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | S-Acetyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. S-Acetyl-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | S-Acetyl-PEG3-Azido Preparation Products And Raw materials |
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