|
|
| | Aminodiphenylmethane hydrochloride Basic information |
| | Aminodiphenylmethane hydrochloride Chemical Properties |
| Melting point | 293-295 °C(lit.) | | Boiling point | 205-207 °C(Press: 4 Torr) | | storage temp. | Inert atmosphere,Room Temperature | | form | powder to crystal | | color | White to Almost white | | Sensitive | Hygroscopic | | Merck | 14,1076 | | BRN | 3914818 | | InChI | 1S/C13H13N.ClH/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12;/h1-10,13H,14H2;1H | | InChIKey | CIHWJRSPVJBHGT-UHFFFAOYSA-N | | SMILES | Cl.NC(c1ccccc1)c2ccccc2 | | CAS DataBase Reference | 5267-34-5(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | HS Code | 29214990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| | Aminodiphenylmethane hydrochloride Usage And Synthesis |
| Chemical Properties | white to off-white crystalline powder | | Uses | Benzhydrylamine Hydrochloride is used as molecular tools to block maturation of nuclear lamin A and decelerate cancer cell migration. | | Synthesis | In the second step, benzophenone oxime (900 mg) was hydrogenated with a solution of concentrated hydrochloric acid (1.84 mL) in ethanol (50 mL) at atmospheric pressure in the presence of 10% Pd/C catalyst (100 mg). Upon completion of the reaction, the reaction mixture was filtered to remove the catalyst and the filtrate was subsequently concentrated. The concentrated residue was suspended in ethyl acetate and the suspension was filtered again to give the final diphenylmethylamine hydrochloride (2.17 g) as a white solid. | | References | [1] Patent: EP2511283, 2012, A1. Location in patent: Page/Page column 91 [2] Patent: US2013/45942, 2013, A1. Location in patent: Paragraph 0379 [3] Patent: JP2015/172077, 2015, A. Location in patent: Paragraph 0187 |
| | Aminodiphenylmethane hydrochloride Preparation Products And Raw materials |
|