| Company Name: |
BOC Sciences |
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16314854226; +8616314854226 |
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AZD3147 manufacturers
- AZD 3147
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- $59.00
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2026-07-27
- CAS:1101810-02-9
- Purity: 99.99%
- Supply Ability: 10g
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| | AZD3147 Basic information |
| Product Name: | AZD3147 | | Synonyms: | AZD3147;1-[4-[4-(1-cyclopropylsulfonylcyclopropyl)-6-[(3S)-3-methylmorpholin-4-yl]pyrimidin-2-yl]phenyl]-3-(2-hydroxyethyl)thiourea;N-[4-[4-[1-(Cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)thiourea;Thiourea, N-[4-[4-[1-(cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)-;(S)-1-(4-(4-(1-(cyclopropylsulfonyl)cyclopropyl)-6-(3-methylmorpholino)pyrimidin-2-yl)phenyl)-3-(2-hydroxyethyl)thiourea;N-[4-[4-[1-(cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)-thiourea;AZD 3147, 10 mM in DMSO;AZ-12600000 | | CAS: | 1101810-02-9 | | MF: | C24H31N5O4S2 | | MW: | 517.66 | | EINECS: | | | Product Categories: | | | Mol File: | 1101810-02-9.mol |  |
| | AZD3147 Chemical Properties |
| Boiling point | 696.7±65.0 °C(Predicted) | | density | 1.45±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: <100 mM; Ethanol: >1 mg/ml; Hydrochloric Acid: <100 mM | | form | A solid | | pka | 11.71±0.70(Predicted) | | color | Off-white to light yellow |
| | AZD3147 Usage And Synthesis |
| Uses | AZD3147 is a selective dual inhibitor of mTORC1 and mTORC2 with physiochemical and pharmacokinectic properties suitable for clinical applications. | | in vivo | The pharmacokinetic parameters of AZD3147[1].
| Parameter | Mouse | Dog | | CL (mL/min/kg) | 78 | 16 | | Vss (L/kg) | 2.3 | 2.2 | | t1/2(h) | 0.9 | 1.9 | | F% | 61 | 73 | |
| | IC 50 | mTORC1; mTORC2 |
| | AZD3147 Preparation Products And Raw materials |
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