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TargetMol |
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| | 25C-NBOH (hydrochloride) Basic information |
| | 25C-NBOH (hydrochloride) Chemical Properties |
| solubility | DMF: 10 mg/ml; DMF:PBS (pH 7) (1:10): 0.09 mg/ml; DMSO: 3 mg/ml; Ethanol: 5 mg/ml | | form | A crystalline solid |
| | 25C-NBOH (hydrochloride) Usage And Synthesis |
| Description | 2C-C is a 2,5-dimethoxyphenethylamine with a chlorine atom at the four position of the aromatic ring. A known hallucinogen, this compound stimulates monoamine receptor activity while inhibiting the re-uptake of serotonin and norepinephrine.1,2 25C-NBOH is a derivative of 2C-C having an N-(2-hydroxybenzyl) addition at the amine. It is a potent agonist of serotonin receptors that shows selectivity for 5-HT2A over 5-HT2C (EC50s = ~ 0.40 and 15 nM, respectively).3 This product is intended for forensic and research applications. | | Uses | 25C-NBOH (Hydrochloride) is a derivative o f 25C-NBOH (CAS# 88441-15-0) which is a hallucinogen that stimulates monoamine receptor activities and at the same time inhibits the re-uptake of serotonin (CAS# 153-98-0) and norepinephrine. Intended for forensic and research use. | | References | 1. Nonaka, R., Nagai, F., Ogata, A., et al. In vitro screening of psychoactive drugs by [35S]GTPγS binding in rat brain membranes Biol. Pharm. Bull. 30(12),2328-2333(2007).
2. Nagai, F., Nonaka, R., and Satoh Hisashi Kamimura, K. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain Eur. J. Pharmacol. 559(2-3),132-137(2007).
3. Hansen, M., Phonekeo, K., Paine, J.S., et al. Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists ACS Chem. Neurosci. 5(3),243-249(2014). |
| | 25C-NBOH (hydrochloride) Preparation Products And Raw materials |
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