13,14-dihydro-15-keto Prostaglandin D1 Exclusive manufacturers
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| | 13,14-dihydro-15-keto Prostaglandin D1 Exclusive Basic information |
| | 13,14-dihydro-15-keto Prostaglandin D1 Exclusive Chemical Properties |
| Boiling point | 537.2±35.0 °C(Predicted) | | density | 1.072±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 50 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 2 mg/ml | | pka | 4.78±0.10(Predicted) |
| | 13,14-dihydro-15-keto Prostaglandin D1 Exclusive Usage And Synthesis |
| Description | Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2. 13,14-dihydro-15-keto Prostaglandin D1 (13,14-dihydro-15-keto PGD1) is the theoretical metabolite of PGD1 via the 15-hydroxy PG dehydrogenase metabolic pathway. No biological studies for this compound have been reported. | | Uses | 13,14-Dihydro-15-keto prostaglandin D1 is a derivative of prostaglandin D1[1]. | | Definition | ChEBI: 13,14-dihydro-15-keto Prostaglandin D1 is a prostanoid. | | References | [1] Amagai Y, et al. Dihomo-γ-linolenic acid prevents the development of atopic dermatitis through prostaglandin D1 production in NC/Tnd mice. J Dermatol Sci. 2015 Jul;79(1):30-7. DOI:10.1016/j.jdermsci.2015.03.010 |
| | 13,14-dihydro-15-keto Prostaglandin D1 Exclusive Preparation Products And Raw materials |
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