2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)-

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2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)- manufacturers

  • CHBO4
  • CHBO4 pictures
  • $50.00
  • 2026-07-27
  • CAS:98991-32-3
  • Purity: 98.02%
  • Supply Ability: 10g
2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)- Basic information
Product Name:2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)-
Synonyms:2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)-;(2E)-1-(4-bromophenyl)-3-(4-fluorophenyl)prop-2-en-1-one;1-(4-bromophenyl)-3-(4-fluorophenyl)prop-2-en-1-one;CHBO4;4-Fluoro-4′-bromochalcone, CAS 98991-32-3
CAS:98991-32-3
MF:C15H10BrFO
MW:305.14
EINECS:
Product Categories:
Mol File:98991-32-3.mol
2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)- Structure
2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)- Chemical Properties
Melting point 133~135℃
Boiling point 400.6±45.0 °C(Predicted)
density 1.451±0.06 g/cm3(Predicted)
Safety Information
MSDS Information
2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)- Usage And Synthesis
UsesCHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research[1].
IC 50hMAO-B: 0.031 μM (IC50); hMAO-B: 0.010 μM (Ki)
References[1] Thomas Parambi DG, et al. Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: Synthesis, biochemistry, and molecular dynamics study. Comput Biol Chem. 2023 Aug;105:107899. DOI:10.1016/j.compbiolchem.2023.107899
2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)- Preparation Products And Raw materials
Tag:2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)-(98991-32-3) Related Product Information
2-Propen-1-one, 1-(3-bromo-5-fluorophenyl)- (2E)-1-(4-bromophenyl)-3-(2-methylphenyl)prop-2-en-1-one (2E)-3-(3-bromophenyl)-1-(4-methylphenyl)prop-2-en-1-one (2E)-1,3-bis(3-bromophenyl)prop-2-en-1-one (2E)-3-(4-bromophenyl)-1-(2-fluorophenyl)prop-2-en-1-one (2E)-1-(4-fluorophenyl)-3-(4-methylphenyl)prop-2-en-1-one