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BOC Sciences |
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+1-631-485-4226 |
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| | CPG52364 Basic information |
| Product Name: | CPG52364 | | Synonyms: | CPG52364;CPG-52364(CPG 52364;4-Quinazolinamine, 6,7-dimethoxy-2-[4-(4-methyl-1-piperazinyl)phenyl]-N-[2-(4-morpholinyl)ethyl]-;6,7-dimethoxy-2-[4-(4-methylpiperazin-1-yl)phenyl]-N-(2-morpholin-4-ylethyl)quinazolin-4-amine | | CAS: | 1093135-60-4 | | MF: | C27H36N6O3 | | MW: | 492.61 | | EINECS: | | | Product Categories: | | | Mol File: | 1093135-60-4.mol |  |
| | CPG52364 Chemical Properties |
| form | Solid | | color | White to light yellow |
| | CPG52364 Usage And Synthesis |
| Uses | CPG-52364 (compound 2) is a TLR9 antagonist. CPG-52364 inhibits the HEK293-hTLR9 cell with an IC50 value of 4.6 nM[1]. | | References | [1] Manabu Watanabe, et al. Dihydropyrrolo[2,3-d]pyrimidines: Selective Toll-Like Receptor 9 Antagonists from Scaffold Morphing Efforts. ACS Med Chem Lett. 2014, 5, 11. DOI:10.1021/ml5003184 |
| | CPG52364 Preparation Products And Raw materials |
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