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| | KDM4D-IN-1 Basic information |
| Product Name: | KDM4D-IN-1 | | Synonyms: | KDM4D-IN-1;KDM4D-IN-10r;KDM4D inhibitor 1;KDM4D-IN-1, >98%;Pyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile, 4,5-dihydro-2-methyl-5-oxo-;KDM4DIN1,Histone Demethylase,KDM4D IN 1,Inhibitor,KDM-4D-IN-1,inhibit;2-Methyl-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile;KDM4D-IN-1, 10 mM in DMSO | | CAS: | 2098902-68-0 | | MF: | C11H7N5O | | MW: | 225.21 | | EINECS: | | | Product Categories: | | | Mol File: | 2098902-68-0.mol |  |
| | KDM4D-IN-1 Chemical Properties |
| Boiling point | 366.2±42.0 °C(Predicted) | | density | 1.58±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 6 mg/mL (26.64 mM) | | form | Solid | | pka | 10.33±0.20(Predicted) | | color | Light yellow to khaki |
| | KDM4D-IN-1 Usage And Synthesis |
| Uses | KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM. | | IC 50 | KDM4 | | References | [1] Fang Z, et al. Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3201-3204. DOI:10.1016/j.bmcl.2017.05.002 |
| | KDM4D-IN-1 Preparation Products And Raw materials |
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